- N Engl J Med 2022; 387:833-838
A 3-year-old boy presented with abdominal pain and vomiting. He had associated chills without fever, nonbloody and nonbilious emesis, constipation, reduced urinary output, and a decreased activity level.
- N Engl J Med 2022; 387:832-832
A 32-year-old man with daily nitrous oxide inhalant use presented with an inability to walk. MRI of the whole spine revealed hyperintensities in the posterior spinal cord on T2-weighted images.
- EditorialAug 27, 202210.1056/NEJMe2209997
Hospitalization for heart failure, usually due to volume overload, is among the most common reasons for hospitalization worldwide, and decongestion with loop diuretics is the primary focus of treatment in most patients.1 Despite the ubiquity of this clinical scenario in daily practice, high-quality data from randomized trials evaluating...
- Original ArticleAug 27, 202210.1056/NEJMoa2208681
Among older men in Denmark, the incidence of death from any cause at a median follow-up of 5.6 years was not significantly lower among those randomly invited to undergo screening for subclinical cardiovascular disease.
- N Engl J Med 2022; 387:e15
A 13-year-old girl with blurry vision, painful eye movements, and weakness and paresthesias in her left leg was found to have a relative afferent pupillary defect in her left eye (shown in a video).
- N Engl J Med 2022; 387:737-737
A 61-year-old woman with primary biliary cholangitis and Raynaud’s phenomenon was referred to the rheumatology clinic. Tongue telangiectasias, puffy fingers, and nailfold capillary hemorrhage were present.
- N Engl J Med 2022; 387:738-747
A 48-year-old woman was evaluated for abdominal pain. CT showed numerous liver lesions and lung cysts and nodules; liver biopsy revealed an eosinophilic inflammatory infiltrate. A diagnosis was made.
- N Engl J Med 2022; 387:640-640
An 86-year-old woman presented with acute pain on the right side of her abdomen. Computed tomography revealed a distended gallbladder outside the gallbladder fossa and swirling of the cystic artery and duct.
- N Engl J Med 2022; 387:641-650
A 25-year-old woman was evaluated for worsening headaches, photophobia, nausea, vomiting, and blurred vision. MRI revealed hydrocephalus and leptomeningeal enhancement. CSF analysis revealed neutrophilic pleocytosis.
- N Engl J Med 2022; 387:577-579
Health worker burnout, exacerbated by Covid-19, is not only about long hours. It’s about the fundamental disconnect between health workers and the mission to serve that motivates them.
- N Engl J Med 2022; 387:e14
A 74-year-old woman with psoriatic arthritis presented with swelling of the fifth finger. On examination, there were nontender, subcutaneous nodules in the hypothenar region and over the fifth finger.
- N Engl J Med 2022; 387:584-585
For professionals who work with children and adolescents, policies like Florida’s “Don’t Say Gay” law have outsized cruelty — even beyond the enormous harm they will do to the young people we serve.
- N Engl J Med 2022; 387:565-567
This interactive feature about screening for atrial fibrillation in asymptomatic older adults offers a case vignette accompanied by two essays, one supporting screening and the other supporting deferral of screening.
- N Engl J Med 2022; 387:e12
A 51-year-old man with chronic myeloid leukemia who was receiving treatment with nilotinib presented for follow-up with a report that his hair had turned from gray to its original brown color.
Understanding Covid Vaccine Efficacy over Time — Bridging a Gap Between Public Health and Health CareN Engl J Med 2022; 387:483-485
It’s now feasible to track, for each patient seen at a health care facility, which Covid-19 vaccine they received when and what their clinical evaluation revealed.