A collection of articles and other resources on epidemic outbreaks, including management guidelines and commentary.
EPIDEMICS GOING VIRAL: INNOVATION VS. NATURE
April 27, 2018
8:00 am – 12:45 pm ET
View the recorded video.
Presented by the New England Journal of Medicine and the Massachusetts Medical Society, the live-streamed event brought together a group of renowned researchers, clinicians, public health officials, and others with first-hand experience dealing with epidemics, to explore the complex challenges of global health emergencies, as well as potential solutions.
In this year’s Shattuck Lecture, Bill Gates highlighted the important role of innovation in mitigating the impact of future epidemics. Learn how advances in vaccine development and the sequencing of pathogens, along with other steps in global health preparedness, can accelerate prevention and control of pandemic diseases.
Web event recording now available: If you missed the event, you can access the video.
Zika Virus and Its Associated Diseases
D. Musso, A.I. Ko, and D. Baud
Zika is a mosquito-borne flavivirus that can cause congenital defects, including microcephaly. Although most Zika virus infections are asymptomatic, rash, fever, arthralgia, myalgia, and conjunctivitis can develop in some people. The Guillain–Barré syndrome occurs in 2 to 3 patients per 10,000 with Zika virus infection.
- Review Article Zika Virus and Its Associated Diseases D. Musso, A.I. Ko, and D. Baud
Randomized, Controlled Trial of Ebola Treatments
S. Mulangu and Others
Ebola transmission has been ongoing in the Democratic Republic of Congo since August 2018. In this trial of MAb114, REGN-EB3, remdesivir, and ZMapp (as the control), mortality from Ebola virus disease was lower in the MAb114 and REGN-EB3 groups than in the other groups.
PrEParing to End the HIV Epidemic
D.S. Kazi, I.T. Katz, and A.K. Jha
A new California law will allow pharmacists to furnish a 30-to-60-day supply of preexposure prophylaxis for HIV without a prescription from a physician. Though the law is imperfect, it’s an important step forward and could provide a road map for the rest of the country.
- Original Article Randomized, Controlled Trial of Ebola Treatments S. Mulangu and Others
Innovation for Pandemics
What the world needs is a coordinated global approach to pandemics that will work regardless of whether the next pandemic is a product of humans or of nature. Specifically, we need better tools, an early detection system, and a global response system.
- Perspective Shattuck Lecture Innovation for Pandemics B. Gates