More than 6 million adults in the United States have heart failure, accounting for at least 800,000 hospitalizations annually.1 More than half of these persons have heart failure with a preserved left ventricular ejection fraction.1 As the population ages, the overall prevalence of patients with heart failure and a preserved ejection fraction is increasing.1,2 Heart failure with a preserved ejection fraction is associated with substantial functional and quality-of-life impairments that are at least equivalent to those of patients with heart failure and a reduced ejection fraction.2 One-year mortality among patients with heart failure and a preserved ejection fraction is between . . .
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This editorial was published on August 27, 2022, at NEJM.org.
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