Ischemic cardiomyopathy represents the pathophysiological convergence of two growing clinical problems: atherosclerotic coronary artery disease and congestive heart failure. When a patient presents with congestive heart failure, it is incumbent on clinicians to undertake an etiologic workup that includes evaluation for a diagnosis of coronary artery disease1; simply establishing a diagnosis of coronary artery disease has been associated with greater use of guideline-directed medical therapies among patients with congestive heart failure.2 When it is severe, coronary artery disease is often assumed to be the cause of left ventricular dysfunction. Apart from the accuracy of that assumption, a further open question . . .
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This editorial was published on August 27, 2022, at NEJM.org.
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