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Subacute Combined Degeneration from Nitrous Oxide Use

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  • Joseph Y. Yoon, M.D.,
  • and Joshua P. Klein, M.D., Ph.D.

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A 32-year-old man with daily nitrous oxide inhalant use presented with an inability to walk. MRI of the whole spine revealed hyperintensities in the posterior spinal cord on T2-weighted images.

Joseph Y. Yoon, M.D.
Mount Sinai Hospital, New York, NY

Joshua P. Klein, M.D., Ph.D.
Brigham and Women’s Hospital, Boston, MA

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