Formerly known as Devic’s disease, this relapsing, demyelinating disorder of the central nervous system encompasses six syndromes and is associated with aquaporin-4 autoantibodies. Effective treatment prevents relapses.
Funding and Disclosures
Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.
We thank Mr. Seth Lambert and Mr. Bryce Bergene, Mayo Clinic, for assistance with earlier versions of the figures.
Print Subscriber? Activate your online access.