- N Engl J Med 2022; 387:737-737
A 61-year-old woman with primary biliary cholangitis and Raynaud’s phenomenon was referred to the rheumatology clinic. Tongue telangiectasias, puffy fingers, and nailfold capillary hemorrhage were present.
- N Engl J Med 2022; 387:260-260
A 26-year-old woman presented with sore throat, pain while swallowing, shortness of breath, and fever. Marked swelling of the posterior oropharynx was observed on physical examination, and CT of the neck was performed.
- N Engl J Med 2022; 387:e4
A 46-year-old man presented with tinnitus and dizziness after a backward fall from a 2-m height. CT imaging showed fractures of the occipital and right temporal bones with pneumolabyrinth and pneumocochlea.
- N Engl J Med 2022; 387:83-85
This interactive feature about recurrent acute otitis media in a young child offers a case vignette accompanied by two essays, one supporting insertion of tympanostomy tubes and the other supporting conservative medical management.
- N Engl J Med 2022; 386:809-811
The highest burden of dental and oral disease is shouldered by marginalized and chronically underserved groups. Moving forward, we will need to forge a path for oral health care that prioritizes overall health, prevention, expanded access, affordability, and equity.
- N Engl J Med 2022; 386:e15
An 18-year-old man with hemophilia A presented with throat discomfort and a recent neck hematoma. The physical examination showed an anterior neck ecchymosis and multiple pharyngolaryngeal hematomas on laryngoscopy. The patient was treated with recombinant factor VIII, and his symptoms and hematomas resolved.
- N Engl J Med 2022; 386:583-590
A 55-year-old man was evaluated in the rheumatology clinic because of bilateral hearing loss and eye redness. He had had fatigue and intermittent body aches for 2 months and had lost 5 kg of weight over a 6-month period. There was redness in both eyes and grossly reduced hearing in...
- N Engl J Med 2022; 386:290-293
Photographer Graciela Iturbide captures death and suffering, using her camera to protect herself emotionally from the painful events she witnesses. What can a young surgeon learn from her about aesthetic distance and empathy in medicine?
- N Engl J Med 2022; 386:102-103
In this story, a runner-up in the 2021 NEJM Medical Fiction Contest, an intern and her medical school classmates take a much-needed break on the Maine coast as they struggle to find their sea legs in the world of medicine.
- N Engl J Med 2022; 386:79-79
A 48-year-old woman presented with fatigue and painful, swollen, whitened gums. Her white-cell count was 225,000 per cubic millimeter, and peripheral-blood flow cytometry and bone marrow biopsy revealed 89% myeloblasts. A diagnosis of acute monocytic leukemia was made, and the gingival swelling abated with chemotherapy.
- N Engl J Med 2021; 385:e82
A 38-year-old man presented to the otolaryngology clinic with a long history of difficulty in breathing through his right nostril. Rhinoscopy and computed tomographic imaging showed an inverted ectopic tooth in the nasal cavity.
- N Engl J Med 2021; 385:1700-1710
A 68-year-old man was admitted with painful mouth ulcers and weight loss of 6 weeks’ duration. The ulcers had worsened despite treatment with acyclovir, prednisone, and colchicine. The blood eosinophil count was increased, and the patient was positive for the HLA-B51 allele. A diagnostic procedure was performed.
- N Engl J Med 2021; 385:1604-1613
A 14-year-old girl presented with progressive swelling of the jaw. Six weeks before this admission, a nonpainful lump in the left lower jaw developed. The mass increased in size, and swelling of the left side of the face and neck developed. A biopsy specimen from the mass showed abundant giant...
- N Engl J Med 2021; 385:1511-1520
A 21-year-old man with sickle cell trait presented with sore throat, epistaxis, and petechiae of the oropharynx. The hemoglobin level was 9.8 g per deciliter, the platelet count 1000 per microliter, and the white-cell count 670 per microliter. A test for SARS-CoV-2 RNA was positive. A diagnostic test was performed.
- N Engl J Med 2021; 385:e52
Placement of a double-lumen endotracheal tube is an airway management technique that permits isolation and selective ventilation of an individual lung. This video demonstrates placement of a double-lumen endotracheal tube, which is indicated for the prevention of damage to or contamination of a healthy lung.
- N Engl J Med 2021; 385:e33
A 50-year-old man presented to the dental clinic with a 1-month history of fever, nasal congestion, and an enlarging ulcer between his front teeth. Biopsy revealed extranodal natural killer T-cell lymphoma.
- N Engl J Med 2021; 385:e23
A 61-year-old man with neurofibromatosis type 1 presented with an enlarging neck mass. Surgical excision was performed, and a diagnosis of a malignant peripheral nerve-sheath tumor was made.